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UK: Cannabis gave me my life back

Richard Gray

Scotland on Sunday

Sunday 01 May 2005

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A BREAST cancer victim has made medical history as the first person in
Scotland to be prescribed cannabis as a treatment for chronic pain.

Former nurse Jeanie Rae, 57, has been taking a purified form of the
controversial drug to treat the agonising nerve damage in her right arm
caused by an operation and radiotherapy to beat her cancer.

The pain left her virtually imprisoned in her home in Balfron,
Stirlingshire, for nearly four years because she could not bare even the
lightest touch.

Standard medications given to her to help deal with the suffering had
little effect. But last year she was offered the cannabis-based drug
Sativex by doctors at the pain management clinic in Gartnaval Hospital,
Glasgow, as part of a clinical trial.

Rae is now one of the first people in the UK to be given the drug on
prescription after doctors allowed her to continue taking it after the trial.

A few sprays of the drug under her tongue each day has enabled Rae to lead
a normal life.

"Before, the pain was totally restricting my life and what I could do,"
said the mother of two. "It was so bad that I could not bare to have
someone touch me or even brush against my arm in the street.

"When the doctors suggested that cannabis might be of benefit I wasn't
sure, but I knew I did not want to keep living like that. Within a week of
taking it I started noticing a big difference - I felt infinitely better."

Earlier this month, Canada became the first country in the world to approve
a cannabis-based painkiller when health bosses gave Sativex the green light
for use.

It was given approval for the symptomatic relief of pain in MS sufferers,
and the UK's medicine authorities are currently considering a similar
application. Doctors hope the drug will then be approved for prescription
for other types of chronic pain.

But Rae has been allowed to use the drug on prescription as part of an
extended 'open label' trial since the initial three-month clinical trial
finished last year.

As the wife of a doctor in a quiet rural village, she said she was wary
about taking the drug. She said: "As someone who had never smoked or taken
cannabis before, I did not want to become addicted to it.

"There is a lot of controversy surrounding cannabis because it is an
illegal drug, but in comparison to other drugs it is quite tame."

Rae was diagnosed with breast cancer five yeas ago, forcing her to give up
her job as a nurse at the Western General Hospital in Glasgow.

Her husband Allan, a retired doctor, and their sons Fraser, 36, and Neil,
32, have supported her after she had a lumpectomy to remove cancerous cells
from her breast.

The surgeons also removed lymph glands from under her right arm, but
together with radiotherapy it caused her nerve endings to become inflamed
and damaged. Each day Rae must take about 10 sprays of Sativex to ease her
pain - less than a quarter of the maximum daily dose. But she admits it
does have some side-effects.

She said: "It does make me sleepy and hungry - it gives me the munchies."

Multiple sclerosis sufferers have been campaigning for years to be allowed
to use cannabis to ease their symptoms. One sufferer, Biz Ivol, from
Herston, South Ronaldsay in Orkney, sparked a furious debate when she
admitted making cannabis-laced chocolates for other patients with the same
condition.

She later stood trial for the possession and supply of cannabis in 1997 but
was admonished by the court after admitting growing cannabis plants to
relieve her pain.

At the time, the British Medical Association appealed for leniency for MS
sufferers facing drug charges for using cannabis. Another case against Ivol
was abandoned last year after her health began to fail and she died in
September last year.

Paul Cruikshank, a friend of Ivol and a member of the Legalise Cannabis
Alliance, said: "Patients should be able to get hold of a medicine without
fear of being prosecuted. Putting people in jail for using a medicine that
alleviates their pain and symptoms is totally wrong and against their human
rights."

Earlier this year, Home Secretary Charles Clarke ordered a rethink on the
government's decision to downgrade cannabis to a class C drug.

Fears that the psychotic effects of the drug could lead to long-term mental
illnesses such as schizophrenia caused anti-drug campaigners to call for a
reversal of the legislation.

They also fear use of the drug can lead to abuse of other harder drugs.

But Alistair Ramsay, director of Scotland Against Drugs, said distinctions
had to be made between abusing drugs for recreation and using them for
medical need.

He said: "It is hardly surprising that cannabis is having a proper medical
effect on people who suffer pain.

"Other drugs derived from opium like morphine have been used for similar
purposes. It is only when they are used improperly that the problems can
occur. Like many drugs currently available on prescription, doctors will
need to use caution to ensure it is not being misused."

A recent study by researchers at the University of Lausanne in Switzerland
found even cannabis-based medicines used for pain relief can cause symptoms
such as paranoid delusions and severe anxiety.

But Dr Mick Serpell, the consultant who led the Sativex clinical trial at
Gartnaval, believes the drug could help patients with few other choices.

He said: "We had some good results in our patients - it helped about one in
three.

"These are patients who have tried everything else, so to get that kind of
response can help a lot of people who have no other choices. The type of
people who use it to treat pain are totally different from those who use it
for recreation."

 

 

 

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