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UK: GW needs cash infusion after appeal setback

Stephen Foley

The Independent

Saturday 11 Jun 2005

---
GW Pharmaceuticals, the company hoping to launch the UK's first
cannabis-based prescription drug for multiple sclerosis, is facing a cash
crunch, it admitted yesterday.

The company confirmed it had lost its appeal over a regulatory decision
against approval of the drug, and said it will now have to complete an
expensive extra trial to get the under-the-tongue spray, Sativex, on the UK
market.

GW's failure pushes out the likely launch date for Sativex to late 2006 and
delays a milestone payment of UKP17m from its marketing partner, Bayer. The
company has just UKP16m of cash left and is currently spending more than
UKP1m a month.

Its shares were the worst performers on the stock market yesterday, down
25p to 70.5p. They have now fallen more than 40 per cent since it was first
reported this week that the company had failed to overturn the negative
ruling by the regulator, the Medicines and Healthcare Products Regulatory
Agency (MHRA).

GW said it would try to sell the marketing rights to Sativex in Continental
European countries to try to raise funds. Investors should expect a deal by
the end of this year, the company said.

Mike Booth, an analyst at Canaccord, said that he still expected GW to run
out of cash during 2006. "Even if such a deal can be signed in time, we
consider it unlikely that it would provide enough cash to supply adequate
balance-sheet strength in the near term," he said.

The Medicines Commission, the appeals body within the MHRA, upheld last
December's ruling that GW has so far failed to prove that Sativex is an
effective treatment for the spasticity associated with MS. The spray has
been approved for sale in Canada as a treatment for MS pain, and UK patient
groups criticised the ruling yesterday.

Justin Gover, GW's managing director, said: "We didn't get this saga in
Canada, so I don't think you could say we were naive about the regulatory
process, but the reality is that the UK process was much more complex than
anticipated."

Mr Gover ruled out tapping shareholders for more cash to try to shore up
the company's finances. The shares are now 65 per cent below the level at
which GW raised UKP20m in 2003, when directors also sold UKP8.5m of shares.
Geoffrey Guy, the company's founder and chairman, sold UKP5m.

 

 

 

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