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Israel:Cannabis against Cancer

Israel Today

Monday 12 Sep 2005

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While there is still no real cure for cancer, every day researchers
move a step closer to finding that cure. Twenty-five-year old Natalya
Kogan, a Ph.D. candidate at the Hebrew University of Jerusalem,
working under the supervision of Prof. Raphael Meshulam, recently
proved that extract from the cannabis plant is able to help heal
cancer within the organism.

Kogan, who immigrated from the Ukraine 10 years ago, developed a new
compound known as guinniodic cannabinoids, which is similar to
several anti-cancer medications such as Daunomycin. Whereas
Daunomycin produces negative side effects in the heart, Kogan's tests
have proven the new compound to be much less harmful, even reducing
the volume of cancer, which it did during animal testing.

What makes guinniodic cannabinoids compound so different is that it
forms a complex with the enzyme Topoisomerase II, which is
responsible for mitosis (when two new nuclei form with the same
number of chromosomes as the nucleus from which they're formed). This
specifically stops the division of cells and growth of the tissues,
as compared to most of today's anti-cancer substances that are less
selective in their action. These substances also reduce the blood
supply to the cancer tissue.

While Kogan continues her research to discover mechanisms and modes
of action for these substances, in the interim the substances
themselves have a high potential for future anticancer medications.
Kogan received the Kaye-Innovation Prize from the university for her research.



 

 

 

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