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UK: GW Pharma says Sativex shows 'encouraging results' for MS spasticity

Life Style Extra

Tuesday 03 Oct 2006

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LONDON (AFX) - GW Pharmaceuticals PLC said that results from two Phase
III studies of its cannabis-based drug Sativex showed a 'significant
reduction' in symptoms of spasticity in patients with multiple sclerosis.

The outcome of the studies in spasticity and bladder dysfunction, both
symptoms of MS, were first reported by GW earlier this year.

The MS spasticity study, which evaluated 337 patients over a 15 week
period, showed a significant reduction in symptoms of spasticity in
patients with advanced MS who had severe levels of spasticity despite
ongoing treatment with the best available anti-spasticity medications.

In addition 36 pct of these patients reported at least a 30 pct
improvement in their spasticity symptoms, which was statistically
significant.

Sativex-treated patients also reported improvements in secondary
endpoints such as sleep assessments at clinic visits; a timed 10-metre
walk, quality of life measures, spasm severity and bladder symptoms.

Professor Christine Collin, lead investigator in the study said 'This
study shows encouraging results in a patient population with a high
level of unmet medical need.'
http://www.lse.co.uk/

 

 

 

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