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UK: Scientists still at odds over risks and benefits of taking

Lorna Duckworth

The Independent

Monday 25 Jun 2001

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More adults use cannabis in Britain than in any other European state and
almost half of the nation's teenagers are thought to have smoked the drug
by the time they leave school.

But the debate over the health impact of cannabis is highly controversial,
with supporters of the drug claiming it has few harmful effects and
opponents warning it can do serious damage.

The adverse effects for regular users, and the medicinal benefits for
patients with chronic conditions such as multiple sclerosis, are still not
fully proved, partly because the drug has more than 400 active ingredients.

Cannabis users take the drug because of its mildly sedative effect, which
leads to lower blood pressure, increased appetite, feelings of relaxation
and increased sociability.

But if cannabis is smoked, people have all the long-term risks of tobacco
such as mouth and lung cancers, bronchitis and increased risk of heart
attacks.

In some first-time users it can provoke anxiety, panic and suspicion. There
is also evidence that, in extreme cases, it can produce severe mental
disturbance, and precipitate or aggravate schizophrenic attacks.

Long-term side-effects include distorted perception, slower reaction times,
impaired co-ordination and driving skills, and lack of motivation.

Some research has suggested that heavy users can suffer acute mental
problems, loss of control, irrational fears and depersonalisation. Concerns
have also been raised that plant breeding has made the drug many times more
potent than it was in the 1960s.

Some people argue cannabis can lead to use of hard drugs such as heroin,
but this is not true for most users.

Dr Claire Gerada, a specialist in drugs, said: "Cannabis is undoubtedly
safer than heroin or cocaine. But if the constraints are relaxed, I would
be concerned about increased use of the drug and more problems with
side-effects as people use it for longer."

Evidence that cannabis has a medicinal benefit led the House of Lords
Science and Technology Committee to recommend in 1998 that it should be
used for therapeutic purposes. But the Government is awaiting the results
of clinical trials before deciding whether cannabis extracts should be
prescribed to patients with multiple sclerosis, to help ease their muscle
spasms and tremors, or to reduce the side-effects of chemotherapy in cancer
patients.

America's Food and Drug Administration has approved the oral use of
dronabinol, a cannabis derivative, for people with Aids.

Cannabis analogues have been shown to prevent seizures in epileptic
patients when given in combination with prescription drugs. Claims have
also been made for the drug's use in treating asthma, strokes, Parkinson's
disease, Alzheimer's disease, alcoholism, insomnia and glaucoma.

 

 

 

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