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Scientists develop cannabis spray

Chris Gray

BBC

Monday 11 Dec 2000


Scientists have developed cannabis in a spray form which could become
available on the NHS. The breakthrough could pave the way for cannabis
being used, under medical supervision, in aerosols and injections.

Professor Roger Pertwee, Britain's leading researcher into the medical
benefits of cannabis, believes this approach would be more acceptable
to doctors. GPs have opposed the use of the drug because it had to be
smoked, which risks causing cancer, or eaten, which is an unreliable
method of taking the drug.

Now Prof Pertwee believes the cannabis could be available through the
National Health Service within five to 10 years - if not sooner. The
House of Lords' science and technology committee has recommended the
drug be made available now for medical purposes. The UK Government -
through the Medical Research Council - is currently carrying out a £1m
trial involving 600 multiple sclerosis patients to assess the medical
benefits of the drug.

Prof Pertwee, a reader in neuropharmacology at Aberdeen University, is
recognised as the country's leading researcher into the medical
benefits of cannabis. He is also secretary of the International
CannabisResearch Society. His team's research has already attracted
the interest of major drug companies in the UK and the USA, where some
states allow cannabis to be used medically.

Prof Pertwee, who has been researching cannabis for 30 years, believes
"thousands" of Multiple Sclerosis patients in the UK are already using
the drug to relieve their chronic pain and muscle spasms.

"I agree with the government that more data should be available before
prescribing the drug," he said.

"But having said that I would make cannabis available on the NHS now
because a great many people are using it to relieve chronic pain and
they are doing that through the black market."

"I would rather they usedcannabis under medical supervision."

He has developed and patented the new cannabis compound in
collaboration with Boston-based Dr Raj Razdan and Virginia-based Dr
Billy Martin.

"Water soluble compounds also make the delivery of the drug easier and
less toxic," said Prof Pertwee.

"If we can get rid of some of the unwanted effects of cannabis it may
be able to help agreat many conditions."

"If we can't then its benefits will be limited to relieving chronic
pain."

He is currently working on removing the "high" from cannabis, a step
which involves work on the body's nervous system.

"Unfortunately the same receptor upon which cannabis acts is also the
same target for the pain it is trying to relieve," said Prof Pertwee.

"But it may be possible to have target drugs which block out or
minimise thehigh of cannabis but allow its pain-relieving qualities to
work."

The UK Government banned the medically prescribed use of cannabis in
1971, but inrecent years there has been a growing reluctance by
prosecutors to take such users to court.

 

 

 

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