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Marijuana helps MS patients alleviate pain, spasms

Kathleen Doheny

Reuters

Monday 19 Aug 2002

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SAN DIEGO (Reuters Health) - Cannabis, or marijuana, is an effective drug
that can help patients with multiple sclerosis (MS) to reduce debilitating
pain and muscle spasms, according to a London researcher who presented his
findings Sunday at the 10th World Congress on Pain.

"So many of our patients told us they use cannabis," said Dr. M. S. Chong,
a neurologist at King's College Hospital, London, that he and his
colleagues decided to study its effectiveness and how widespread the use of
it is among MS patients.

While a Scottish study recently reported that about 8% of MS patients use
cannabis, Chong's team found that about 43% of 100 MS patients who answered
their questionnaires did so. Of those, 53% said they began to use it after
the diagnosis was made. Of those who never used it, 76% said they would do
so if the drug were legalized.

About half the patients who tried marijuana continued to use it regularly
to relieve symptoms. They did so, they said, because it works. Nearly three
quarters of current users said it worked to relieve spasms; more than half
said it helped to relieve pain.

Multiple sclerosis is a chronic, often debilitating disorder of the central
nervous system. Symptoms vary from numbness of the limbs to paralysis,
according to the National Multiple Sclerosis Society. Up to 55% of those
with MS suffer pain, muscle spasms or both, Chong says.

"The more disabled the patient, the more likely they were to use it," Chong
said. To evaluate disability, Chong's team used a well-respected and
validated disability scale. The level of disability was the strongest
association with marijuana use, he noted, while he found no association
between subjects' use of cigarettes and alcohol and the use of marijuana.

About one third of the patients worked full- or part-time; 69% were married
or cohabiting. The sample was 75% women and 25% men.

The MS patients did not necessarily abuse marijuana. "A lot of patients
said they would just take one dose, at night," Chong stated. But he is not
certain if a dose meant an entire joint or not.

How does it work? "We really don't know," Chong said, but it probably
"enhances our endogenous cannabinoids." Cannabinoid receptors in the brain
have been discovered recently, and were the subject of another Congress
presentation, but their roles are just beginning to be revealed.

The patients who tried marijuana were also on conventional drugs for pain
relief and spasm relief, Chong added. "I think it basically shows a lot of
our conventional drugs are not very good."

 

 

 

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