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UK: Cannabis spray for MS could be just a year away

Nigel Hawkes

The Times

Wednesday 06 Nov 2002

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CANNABIS-BASED drugs could be on the market next year after trials produced
encouraging results, the company responsible said yesterday.

GW Pharmaceuticals, based in Salisbury, has tested the drug on around 350
patients with multiple sclerosis, and shown significant reductions in pain,
jerky movements and sleep disturbances.

The company now plans to submit these results to the Medicines Control
Agency early next year, with a view to having a licence for the drugs by
the end of 2003.

Dr Geoffrey Guy, executive chairman of GW, said the results represented a
major milestone.

In all three trials, the cannabis-based drug, which is taken in the form of
a spray into the mouth, achieved results over and above those derived from
existing treatments, which the patients continued to take alongside the new
drugs.

Five further trials are in progress in which GW is testing the
effectiveness of the drugs against pain caused by cancer and spinal cord
injury, potentially widening the range of conditions it could be used for.

The MS trials are not yet published, but the company said that they had
achieved significant improvements in diminishing pain and improving the
quality of life.

Two drugs have been tested, which contain the active ingredients of
cannabis, tetrahydrocannabinol and cannabidiol, as their principal components.

A spokesman for the Multiple Sclerosis Society said: 'These preliminary
trial results appear very encouraging and we look forward to seeing the
full results reviewed.

'In the meantime we continue to argue that people should not be
criminalised for using a drug which can alleviate those often painful
symptoms and have asked the police and prosecuting authorities to deal with
cases sympathetically.'

The Medicinal Cannabis Research Foundation said it was delighted the trials
had been successfully completed and urged that the benefits be brought to
patients without delay. Lord Rea, lead trustee of the foundation, said:
'This is great news. The patients in the Phase III studies carried out by
GW Pharmaceuticals appear to have gained significant medical benefit.'

While based on the same chemicals that provide a 'high' when smoked, the
new drugs are likely to disappoint anybody expecting a similar result. They
have been designed to produce minimal psychoactive effects.

 

 

 

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