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UK: MS Study May Force Rethink On Cannabis

Dave Blackhurst

The Sentinel, Staffordshire

Friday 11 Jul 2003

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Multiple sclerosis patients in Staffordshire and Cheshire have completed a
research project which could force the Government to make cannabis legal
for sufferers all over the UK. They are under the care of the University
Hospital of North Staffordshire which is one of six centres in Britain
leading the study to see if the banned drug can ease their pain.

For the past year, 19 patients have been taking up to 10 capsules a day
without being told if they contain the drug or a placebo - a substitute
with no active ingredients.

Doctors examined the "guinea pigs" every few weeks to look for any
improvement in symptoms such a muscle stiffness and lack of movement.

Now the trial has ended, the results from all the lead centres - plus 24
smaller hospitals involved - are being collected and analysed by experts
behind what is the first research of its kind.

They will be double-checked by objective referees before being published
towards the end of the year.

MS sufferers have long admitted illegally buying cannabis from dealers
because they are convinced it brings relief.

But until now all the evidence has been anecdotal and Ministers refused to
make it available in purely medical circumstances.

Following years of lobbying by both patients and doctors, however, the
Government authorised the research and allowed cannabis plants to be grown
at secret locations under tight security to be given patients.

Dr Clive Hawkins, consultant neurologist at the Hartshill hospital and an
adviser to Whitehall, said: "These are really exciting times and everyone
is waiting with baited breath to see what answers this research brings.

"If it does produce evidence of benefits to patients, it will throw up some
challenging issues for Ministers as we move into the winter.

"I am delighted this hospital and our patients have been involved in
something as important and potentially historic as this."

Patients had to agree not to drive during the trial because of potential
drowsiness. A Home Office licence was needed in each case and the patients
carried special ID cards to protect them from prosecution for possession if
stopped by the police.

They were banned from travelling abroad during the year because their
criminal immunity covered only Britain.

Researcher Dr Emma Pye said: "Some people declined to take part because
they feared they might have been on the placebo and so would have been
taking nothing to control symptoms.

"But despite the restrictions, there was a very small drop-out rate. The
patients are those with the most severe symptoms of all MS sufferers and
included some in wheelchairs. They are from Staffordshire, South Cheshire
and Shropshire.

"They all felt they had benefited from getting more intensive medical
supervision than they would normally expect and a few said they felt spaced
out without possibly knowing what group they were in."

The cannabis-takers themselves were split into sub-groups - one taking pure
tetrahydrocannaboil which is its active chemical and the other given
capsules with the drug in its crude form. That is to see if there are other
substances in cannabis which also work.

The patients will eventually be told which group they were in.

dave.blackhurst@thesentinel.co.uk

 

 

 

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