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UK: NHS patients to be given cannabis

BBC Online

Wednesday 20 Aug 2003

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NHS patients are to be given cannabis as part of a government-funded trial.

The study, which is being run by the Medical Research Council, aims to find
out if the drug really can help to relieve pain.

Scientists will randomly select 400 patients from 36 hospitals across
England to take part in the study.

They will be given one of four pills after undergoing surgery, two of which
will be a form of cannabis.

Controlled study

They will receive a capsule containing standardised cannabis extract or a
capsule containing tetrahydrocannabinol - the active ingredient in cannabis.

The remaining patients will receive either a standard pain-relieving drug
or a dummy pill.

Researchers will ask the patients about their pain and general well-being
at least once every hour while they are awake, over a six hour-period. The
patients will be able to request additional pain relief at any time.

The researchers will then be able to compare the experiences of patients in
each of the four groups and, hopefully, determine whether the cannabis-based treatments are effective.

The £500,000 trial is being headed by scientists at Imperial College London.

"Many patients and clinicians want an answer to the question of whether
cannabis is effective at relieving pain," said Dr Anita Holdcroft, who will
lead the study.

"We need to assess the scientific merits of some of the anecdotal evidence
and we need to do this in the same way as any other experimental pain
treatment.

"This is a proper study in a clinical setting where patients can be
routinely monitored, using an oral capsule containing a prescribed dose."

Medical claims

Studies have suggested that cannabis and cannabis-based medicines can help
to relieve pain.

Last year, a small trial involving 34 British patients with multiple
sclerosis, spinal cord injury and other conditions causing severe pain,
found that using cannabis-based treatments reduced their pain and helped
them to sleep more soundly.

Researchers have also found evidence to suggest it can help to reduce the
side effects of chemotherapy treatment given to cancer patients.

In the United States, the Food and Drug Administration has approved the
oral use of dronabinol, a cannabis derivative, for people with Aids.

There is evidence that cannabis may stimulate the appetites of Aids
patients with wasting disease.

It may also help relieve the pain of menstrual cramps and childbirth.

Claims have also been made for its use in treating asthma, strokes,
Parkinson's Disease, Alzheimer's Disease, alcoholism and insomnia.

However, opponents of the use of cannabis point to the fact that it damages
the ability to concentrate and, if smoked, may increase the risks of
developing lung cancer.

The British Medical Association has said that only cannabinoids - part of
the cannabis plant - should be used in medicine.

 

 

 

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