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UK: If cannabis is safe, why am I psychotic?

Steve Boggan

The Times

Wednesday 07 Jan 2004

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Weeks before the drug is downgraded from Class B to Class C comes new
evidence that cannabis-induced psychosis is the bigest problem facing inner
city mental health services

THERE WAS SOMETHING horribly fast and terribly chilling about the onset of
Steve Hammond's psychosis. His father Terry remembers feeling a shiver down
his spine when, sitting in front of the television, Steve turned to him
with a strange look in his eyes and said: "Why did you ring up the BBC?"
"Of course, I told him I hadn't," Terry recalls. "But then Steve said: 'Yes
you did. You rang them up and told them I'm a lazy, useless bastard. And
they've been broadcasting it all day.'"
This was the start of three years of hell for the Hammond family; three
years during which Steve, a bright, handsome and popular 22-year-old,
descended into madness and despair. For Terry it was the moment when he
first saw the illness for himself. For Steve it was a frightening repeat of
an episode a few days earlier when, with no papers to roll a joint, he ate
a chunk of cannabis resin and collapsed in a nightclub toilet. "When I woke
up I heard someone saying: 'It's OK Steve, you can get up now, you're all
right'," he recalls. "When I looked around, there was no one there.

"That's when my voices started and I've had them ever since. I was so
scared you can't imagine. I had voices coming from everywhere - the
ceiling, the floor, in my head. It was the most frightening nightmare you
could imagine, except I was awake."

Steve is one of 210,000 people in the UK who suffer from schizophrenia, and
one of a growing number who believe cannabis caused their condition. Ten
years ago psychiatrists would have disagreed with him. But three weeks
before the Government is due to reclassify cannabis from a Class B to a
Class C drug, that view has changed dramatically. Some of Britain's most
senior psychiatrists say the drug is now the "No 1 problem" facing mental
health services. Psychiatrists in inner-city areas speak of cannabis being
a factor in up to 80 per cent of schizophrenia cases, and mental health
specialists are bracing themselves for an increase in the problem as
reclassification is misinterepreted as an assurance that the drug is safe.

For years psychiatrists have noticed a high level of cannabis use among
people with psychosis, a generic term for schizophrenia, delusional
episodes, manic depression and so on. But it had always been regarded as a
chicken and egg problem; sufferers tended to have behavioural problems as
adolescents and were more likely to use drugs to counter their often
miserable lives. But all that changed two years ago when a group of
researchers had the idea of relating cannabis and psychosis to the Dunedin
group, a continuing long-term study of 1,000 children - now adults - in New
Zealand. They found that those who used cannabis by the age of 15 were more
than three times as likely to develop illnesses such as schizophrenia.

Since then, other control groups - including a 1987 survey of 50,000
conscripts in the Swedish army and another study in Amsterdam - have been
examined again with the drug in mind, and they have all shown that cannabis
use increases the likelihood of psychosis by up to 700 per cent.

Robin Murray, a professor at the Institute of Psychiatry and a consultant
psychiatrist at the Maudsley Hospital in South London, took part in the
groundbreaking research that first solved the chicken-and-egg problem. His
co-authored report, published a year ago, concluded: "Although most young
people use cannabis without harm, a vulnerable minority experience harmful
outcomes. A tenth of the cannabis users by age 15 in our sample developed
schizophreniform disorder by age 26 compared with 3 per cent of the
remaining cohort. Our findings suggest that cannabis use among
psychologically vulnerable adolescents should be strongly discouraged by
parents, teachers, and health practitioners. Policy makers and lawmakers
should concentrate on delaying onset of cannabis use."

In an interview with The Times, Professor Murray adds: "Unfortunately there
were no experts in psychosis on the committees (the Home Affairs select
committee and the Advisory Council on the Misuse of Drugs) that advised the
Government on re-classifying cannabis. That's not a criticism - at the
time, no one thought there should have been. Since then there have been at
least four studies that show the use of cannabis can significantly increase
the likelihood of the onset of psychosis.

"I would say this is now the No 1 problem facing the mental health services
in inner cities. In south London the incidence of psychosis has doubled
since 1964. There is a terrible drain on resources. Not only are there
people suffering from psychosis who would not be in in-patient beds if they
were not using cannabis, but use of the drug also drastically reduces the
chances of recovery. People who do improve go out on the streets, meet
their old dealer, begin using the drug again and relapse. We're not saying
that the Government shouldn't reclassify cannabis - for most people it
causes no problems - but I am saying that if they're going to do it they
should warn people of the possible downside."

The downside for Steve Hammond, now 25, was three months in a psychiatric
ward and the loss of a promising future. After three years of treatment, he
lives with his parents at their home in Southampton. His paranoia is
controlled by drugs but he still hears voices, is unable to work and
remains afraid to go out alone.

"I can remember it starting as if it were yesterday," he says. "I wouldn't
want to wish that on anyone; it was terrifying. The voices got worse and
worse as the days and months went by. I became completely paranoid. I was
convinced my mind had been taken over by aliens; well, you would - how else
could you explain the voices?

"My mum and dad were great. They convinced me to go into hospital. There
was a bit inside me that said, 'Steve you need help'. When I came out I
felt better, although my voices were still there. I tried different
medications and eventually the doctors found one that suited me, that did
not give me bad side effects. My voices are still there but cognitive
therapy has helped me to understand them. It made me realise that they were
really my own thoughts. The doctor explained to me about how the
communication system in my brain was not functioning correctly. He
explained all about neurotransmitters. It seemed to make perfect sense to
me. It was a revelation and a fantastic relief that I had not been invaded
by aliens.

"I didn't have a clue that cannabis could do this; if I had, I may have had
second thoughts, or at least not smoked so much. I thought it was perfectly
harmless. If it was public knowledge that cannabis can affect your mental
health in this way, young people would be more switched on to recognise the
symptoms or they might make an informed choice not to start at all.

"I have tried smoking cannabis since, but it was terrible. As soon as I
took a couple of puffs it made me feel instantly crazy. It was like putting
on a switch. I don't touch the stuff now."

The voices and hallucinations in schizophrenia result from an excess of the
brain chemical dopamine. Drugs such as cannabis, amphetamines and cocaine
increase the levels of dopamine in the brain. The Lambeth Early Onset (Leo)
service at Lambeth Hospital in south London has a first-onset psychosis
ward where the damaging effects of cannabis on dopamine levels are all too
easy to see.

Young men and women are brought in as early as possible to improve their
chances of recovery with anti-psychotic drugs. In a year, as many as 120
patients pass through the ward - the vast majority admitting to regular
cannabis use.

"It would be wrong to say that cannabis alone causes psychosis," says Paddy
Power, a consultant psychiatrist at the unit. "It's a bit like saying
someone had a heart attack because of a stressful incident when they also
ate too much fatty food, took too little exercise and smoked. In much the
same way, using cannabis can be a major contributory factor in the onset of
psychosis. You are also at greater risk of developing psychosis from
genetic factors, early brain development problems, birth trauma and even
migrating to another country. If you add cannabis, then you have a
dangerous mix.

"Between 70 and 80 per cent of the people who present at our unit have a
history of cannabis use that has probably been a factor in the development
of their psychosis. I wouldn't say that should prevent a reclassification
of the drug, but it would be irresponsible of the Government not to marry
that with an educational programme - particularly for parents and young
people - so users can be made aware of the risks in much the same way as we
are given health warnings over alcohol and tobacco."

The Home Office says its "Frank" anti-drugs campaign includes advice on
cannabis, but its efforts on education timed for the reclassification of
the drug on January 29 could be called into question. It has commissioned
the mental health charity Mentor to produce a million leaflets for
distribution a month after the reclassification - on a budget of just
£50,000. Mentor's chief executive, Eric Carlin, says much more money is
needed if the message that all drugs - including cannabis - are potentially
dangerous is to get to young people. "The area has been neglected," he
says. "We are not yet clearly making the point that if you have a history
of mental illness, or if you are pre-disposed to psychosis, you are playing
Russian roulette by smoking cannabis. Our job is to try to get that message
across."

But isn't reclassifying cannabis from B to C sending a message in itself
that the drug is safe? The Home Affairs select committee that recommended
the reclassification in May 2002 thinks not, even in the light of the new
evidence. David Winnick, one of the MPs on the committee, says its members
stand by their recommendation. "We would not change our view," he says. "I
believe we should be warning people that they should not take any drugs,
including cannabis. But we decided that to continue to criminalise everyone
who takes cannabis would be wrong.

"As opposed as I am to people smoking nicotine, I would not be in favour of
banning that. All we can do is warn people of its dangers. There was no
evidence to suggest that more people would smoke cannabis simply because we
reclassified it, and I don't believe they will."

Terry Hammond, Steve's father, disagrees. "Of course it sends a message,"
he says. "After Steve became psychotic I spoke to a lot of his friends
about cannabis and they all thought it was perfectly safe - and they felt
that the reclassification confirmed that. Since then I have been contacted
by lots and lots of parents who believe cannabis was a major factor in
their sons and daughters slipping into psychosis. I have no doubt it caused
Steve's.

"Most people who smoke cannabis will probably suffer no harm whatsoever.
But for some it will be disastrous. They could sink into Steve's world. And
I wouldn't wish that on anyone."

 

 

 

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