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US: New Study Explains How Pot Kills Cancer Cells

Steve Kubby

The Sierra Times, US

Wednesday 01 Dec 2004

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A new study published in Nature Reviews-Cancer provides an historic and
detailed explanation about how THC and natural cannabinoids counteract
cancer, but preserve normal cells.

The study by Manuel Guzman of Madrid Spain found that cannabinoids, the
active components of marijuana, inhibit tumor growth in laboratory animals.
They do so by modulating key cell-signalling pathways, thereby inducing
direct growth arrest and death of tumor cells, as well as by inhibiting the
growth of blood vessels that supply the tumor.

The Guzman study is very important according to Dr. Ethan Russo , a
neurologist and world authority on medical cannabis: "Cancer occurs because
cells become immortalized; they fail to heed normal signals to turn off
growth. A normal function of remodelling in the body requires that cells
die on cue. This is called apoptosis, or programmed cell death. That
process fails to work in tumors. THC promotes its reappearance so that
gliomas, leukemias, melanomas and other cell types will in fact heed the
signals, stop dividing, and die."

"But, that is not all," explains Dr. Russo: "The other way that tumors grow
is by ensuring that they are nourished: they send out signals to promote
angiogenesis, the growth of new blood vessels. Cannabinoids turn off these
signals as well. It is truly incredible, and elegant."

In other words, this article explains several ways in which cannabinoids
might be used to fight cancer, and, as the article says, "Cannabinoids are
usually well tolerated, and do not produce the generalized toxic effects of
conventional chemotherapies.

Usually, any story that even suggests the possibility of a new treatment
for cancer is greeted with headlines about a "cancer cure" - however remote
in the future and improbable in fact it might be. But if marijuana is
involved, don't expect any coverage from mainstream media, especially since
mainstream editors have been quietly killing this story for the past thirty
years.

That's right, news about the abilility of pot to shrink tumors first
surfaced, way back in 1974. Researchers at the Medical College of Virginia,
who had been funded by the National Institutes of Health to find evidence
that marijuana damages the immune system, found instead that THC slowed the
growth of three kinds of cancer in mice -- lung and breast cancer, and a
virus-induced leukemia.

The Washington Post reported on the 1974 study -- in the "Local" section --
on Aug. 18, 1974. Under the headline, "Cancer Curb Is Studied," it read
in part: "The active chemical agent in marijuana curbs the growth of three
kinds of cancer in mice and may also suppress the immunity reaction that
causes rejection of organ transplants, a Medical College of Virginia team
has discovered." The researchers "found that THC slowed the growth of lung
cancers, breast cancers, and a virus-induced leukemia in laboratory mice,
and prolonged their lives by as much as 36 percent."

"News coverage of the Madrid discovery has been virtually nonexistent in
this country. The news broke quietly on Feb. 29, 2000 with a story that
ran once on the UPI wire about the Nature Medicine article," complained
MarijuanaNews.com editor Richard Cowan , who said he was only able to find
the article through a link that appeared briefly on the Drudge Report Web
page. "The New York Times, The Washington Post, and Los Angeles Times all
ignored the story, even though its newsworthiness is indisputable: a benign
substance occurring in nature destroys deadly brain tumors," added Cowan.

On March 29, 2001, the San Antonio Current printed a carefully
researched, bombshell of a story by Raymond Cushing titled, "POT SHRINKS
TUMORS; GOVERNMENT KNEW IN '74." Media coverage since then has been
nonexistant, except for a copy of the story on Alternet .

It is hard to believe that the knowledge that cannabis can be used to fight
cancer has been suppressed for almost thirty years , yet it seems likely
that it will continue to be suppressed. Why?

According to Cowan, the answer is because it is a threat to cannabis
prohibition . "If this article and its predecessors from 2000 and 1974
were the only evidence of the suppression of medical cannabis, then one
might perhaps be able to rationalize it in some herniated way. However,
there really is massive proof that the suppression of medical cannabis
represents the greatest failure of the institutions of a free society,
medicine, journalism, science, and our fundamental values," Cowan notes.

Millions of people have died horrible deaths and in many cases, familes
exhausted their savings on dangerous, toxic and expensive drugs. Now we
are just beginning to realize that while marijuana has never killed anyone,
marijuana prohibition has killed millions.



 

 

 

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